14. Piezoelectricity and Autoinduction. A.A. Marino & R.O. Becker Clin. Orthop. 100:247-249, 1974.

A relationship between 2 phenomena exhibited by bone matrix, piezoelectricity and auto- induction, is unlikely. Autoinduction demonstrated by others to be diminished following prolonged treatment of the bone matrix with Hcl, and altogether absent with HNO3 demin- eralized bone matrix, has a relatively constant piezoelectric coefficient, d14, and does not depend on either the acid used or the time of exposure. Since prolonged acid treatment destroys the autoinduction property but does not materially affect the bone collagen matrix, it is reasonable to assume that the bone matrix inductive capacity may be associated with some constituent other than collagen alone.